我们提出了高度可行的帕累托优化（HIPPO） - 批处理采集功能，可实现多目标贝叶斯优化方法有效利用并行处理资源。多目标贝叶斯优化（MOBO）是解决昂贵的黑盒问题的非常有效的工具。但是，大多数主板算法被设计为纯粹的顺序策略，而现有的批次方法对于除最小的批量尺寸以外的所有人都非常昂贵。我们表明，通过通过以相似的预测目标值进行惩罚评估来鼓励批处理多样性，Hippo可以便宜地建立大量的信息观点。我们广泛的实验验证表明，河马至少与现有替代方案一样有效，同时产生的计算开销较低，并易于扩展到比文献中目前支持的批次大小要高得多。此外，我们证明了河马在充满挑战的热交换器设计问题上的应用，这强调了我们高度可行的MOBO方法的现实效用。

We address the challenge of building domain-specific knowledge models for industrial use cases, where labelled data and taxonomic information is initially scarce. Our focus is on inductive link prediction models as a basis for practical tools that support knowledge engineers with exploring text collections and discovering and linking new (so-called open-world) entities to the knowledge graph. We argue that - though neural approaches to text mining have yielded impressive results in the past years - current benchmarks do not reflect the typical challenges encountered in the industrial wild properly. Therefore, our first contribution is an open benchmark coined IRT2 (inductive reasoning with text) that (1) covers knowledge graphs of varying sizes (including very small ones), (2) comes with incidental, low-quality text mentions, and (3) includes not only triple completion but also ranking, which is relevant for supporting experts with discovery tasks. We investigate two neural models for inductive link prediction, one based on end-to-end learning and one that learns from the knowledge graph and text data in separate steps. These models compete with a strong bag-of-words baseline. The results show a significant advance in performance for the neural approaches as soon as the available graph data decreases for linking. For ranking, the results are promising, and the neural approaches outperform the sparse retriever by a wide margin.

Machine learning models are typically evaluated by computing similarity with reference annotations and trained by maximizing similarity with such. Especially in the bio-medical domain, annotations are subjective and suffer from low inter- and intra-rater reliability. Since annotations only reflect the annotation entity's interpretation of the real world, this can lead to sub-optimal predictions even though the model achieves high similarity scores. Here, the theoretical concept of Peak Ground Truth (PGT) is introduced. PGT marks the point beyond which an increase in similarity with the reference annotation stops translating to better Real World Model Performance (RWMP). Additionally, a quantitative technique to approximate PGT by computing inter- and intra-rater reliability is proposed. Finally, three categories of PGT-aware strategies to evaluate and improve model performance are reviewed.

Efficient surrogate modelling is a key requirement for uncertainty quantification in data-driven scenarios. In this work, a novel approach of using Sparse Random Features for surrogate modelling in combination with self-supervised dimensionality reduction is described. The method is compared to other methods on synthetic and real data obtained from crashworthiness analyses. The results show a superiority of the here described approach over state of the art surrogate modelling techniques, Polynomial Chaos Expansions and Neural Networks.

In recent years distributional reinforcement learning has produced many state of the art results. Increasingly sample efficient Distributional algorithms for the discrete action domain have been developed over time that vary primarily in the way they parameterize their approximations of value distributions, and how they quantify the differences between those distributions. In this work we transfer three of the most well-known and successful of those algorithms (QR-DQN, IQN and FQF) to the continuous action domain by extending two powerful actor-critic algorithms (TD3 and SAC) with distributional critics. We investigate whether the relative performance of the methods for the discrete action space translates to the continuous case. To that end we compare them empirically on the pybullet implementations of a set of continuous control tasks. Our results indicate qualitative invariance regarding the number and placement of distributional atoms in the deterministic, continuous action setting.

Artificial Intelligence (AI) has become commonplace to solve routine everyday tasks. Because of the exponential growth in medical imaging data volume and complexity, the workload on radiologists is steadily increasing. We project that the gap between the number of imaging exams and the number of expert radiologist readers required to cover this increase will continue to expand, consequently introducing a demand for AI-based tools that improve the efficiency with which radiologists can comfortably interpret these exams. AI has been shown to improve efficiency in medical-image generation, processing, and interpretation, and a variety of such AI models have been developed across research labs worldwide. However, very few of these, if any, find their way into routine clinical use, a discrepancy that reflects the divide between AI research and successful AI translation. To address the barrier to clinical deployment, we have formed MONAI Consortium, an open-source community which is building standards for AI deployment in healthcare institutions, and developing tools and infrastructure to facilitate their implementation. This report represents several years of weekly discussions and hands-on problem solving experience by groups of industry experts and clinicians in the MONAI Consortium. We identify barriers between AI-model development in research labs and subsequent clinical deployment and propose solutions. Our report provides guidance on processes which take an imaging AI model from development to clinical implementation in a healthcare institution. We discuss various AI integration points in a clinical Radiology workflow. We also present a taxonomy of Radiology AI use-cases. Through this report, we intend to educate the stakeholders in healthcare and AI (AI researchers, radiologists, imaging informaticists, and regulators) about cross-disciplinary challenges and possible solutions.

Understanding our brain is one of the most daunting tasks, one we cannot expect to complete without the use of technology. MindBigData aims to provide a comprehensive and updated dataset of brain signals related to a diverse set of human activities so it can inspire the use of machine learning algorithms as a benchmark of 'decoding' performance from raw brain activities into its corresponding (labels) mental (or physical) tasks. Using commercial of the self, EEG devices or custom ones built by us to explore the limits of the technology. We describe the data collection procedures for each of the sub datasets and with every headset used to capture them. Also, we report possible applications in the field of Brain Computer Interfaces or BCI that could impact the life of billions, in almost every sector like healthcare game changing use cases, industry or entertainment to name a few, at the end why not directly using our brains to 'disintermediate' senses, as the final HCI (Human-Computer Interaction) device? simply what we call the journey from Type to Touch to Talk to Think.

Modern mobile burst photography pipelines capture and merge a short sequence of frames to recover an enhanced image, but often disregard the 3D nature of the scene they capture, treating pixel motion between images as a 2D aggregation problem. We show that in a "long-burst", forty-two 12-megapixel RAW frames captured in a two-second sequence, there is enough parallax information from natural hand tremor alone to recover high-quality scene depth. To this end, we devise a test-time optimization approach that fits a neural RGB-D representation to long-burst data and simultaneously estimates scene depth and camera motion. Our plane plus depth model is trained end-to-end, and performs coarse-to-fine refinement by controlling which multi-resolution volume features the network has access to at what time during training. We validate the method experimentally, and demonstrate geometrically accurate depth reconstructions with no additional hardware or separate data pre-processing and pose-estimation steps.

The following article presents a memetic algorithm with applying deep reinforcement learning (DRL) for solving practically oriented dual resource constrained flexible job shop scheduling problems (DRC-FJSSP). In recent years, there has been extensive research on DRL techniques, but without considering realistic, flexible and human-centered shopfloors. A research gap can be identified in the context of make-to-order oriented discontinuous manufacturing as it is often represented in medium-size companies with high service levels. From practical industry projects in this domain, we recognize requirements to depict flexible machines, human workers and capabilities, setup and processing operations, material arrival times, complex job paths with parallel tasks for bill of material (BOM) manufacturing, sequence-depended setup times and (partially) automated tasks. On the other hand, intensive research has been done on metaheuristics in the context of DRC-FJSSP. However, there is a lack of suitable and generic scheduling methods that can be holistically applied in sociotechnical production and assembly processes. In this paper, we first formulate an extended DRC-FJSSP induced by the practical requirements mentioned. Then we present our proposed hybrid framework with parallel computing for multicriteria optimization. Through numerical experiments with real-world data, we confirm that the framework generates feasible schedules efficiently and reliably. Utilizing DRL instead of random operations leads to better results and outperforms traditional approaches.

People living with dementia often exhibit behavioural and psychological symptoms of dementia that can put their and others' safety at risk. Existing video surveillance systems in long-term care facilities can be used to monitor such behaviours of risk to alert the staff to prevent potential injuries or death in some cases. However, these behaviours of risk events are heterogeneous and infrequent in comparison to normal events. Moreover, analyzing raw videos can also raise privacy concerns. In this paper, we present two novel privacy-protecting video-based anomaly detection approaches to detect behaviours of risks in people with dementia. We either extracted body pose information as skeletons and use semantic segmentation masks to replace multiple humans in the scene with their semantic boundaries. Our work differs from most existing approaches for video anomaly detection that focus on appearance-based features, which can put the privacy of a person at risk and is also susceptible to pixel-based noise, including illumination and viewing direction. We used anonymized videos of normal activities to train customized spatio-temporal convolutional autoencoders and identify behaviours of risk as anomalies. We show our results on a real-world study conducted in a dementia care unit with patients with dementia, containing approximately 21 hours of normal activities data for training and 9 hours of data containing normal and behaviours of risk events for testing. We compared our approaches with the original RGB videos and obtained an equivalent area under the receiver operating characteristic curve performance of 0.807 for the skeleton-based approach and 0.823 for the segmentation mask-based approach. This is one of the first studies to incorporate privacy for the detection of behaviours of risks in people with dementia.